Serial 2-photon tomography systems have good resolution but the acquisition session might last anywhere from a few hours, to a few days for galvo-based systems. StitchIt has a tool called syncAndCrunch that pre-processes tiles during acquisition, displays the last completed slice on the web, and automatically stitches the data at the conclusion of acquisition. This is useful since pre-processing of the images is more time consuming than stitching. We have found monitoring the state of the acquisition to be enormously helpful. In the past we have used this to rescue samples that would otherwise have been lost to things like laser instability, too much or too little laser power, incorrect PMT gain, air bubbles on the objective, etc.